Finding the Cure

For nearly 30 years, the Children’s Cancer Institute at Hackensack University Medical Center has stood as a beacon of hope for children and families dealing with pediatric cancer in New Jersey. With more than 100 active oncology and transplant clinical trials currently open, our institute is leading the charge to cure childhood cancer.

Your support for Tackle Kids Cancer helps make these current programs possible.

Treatment of Recurrent Brain and Solid Tumors

  • The Joseph M. Sanzari Children’s Hospital is the primary site participating in a phase I study using 2-hydroxyoleic acid with Dana-Farber Cancer Institute.
  • This drug has been tested in Europe in adults with highly aggressive brain tumors and the results were very impressive.
  • Since this drug is a fatty acid, similar to olive oil, it has very few side effects and is well tolerated in adult patients.
  • This will be the first time this drug will be used in the United States and with children.
  • No proven therapy currently exists for pediatric cancer patients; this study is very promising.

New Jersey Pediatric Neuro-Oncology Board

  • Derek Hanson’s “New Jersey Pediatric Neuro-Oncology Board” will utilize a state-of-the art conferencing system to enable participating physicians from all pediatric oncology centers across New Jersey to present their cases.
  • A panel of experts will review cases.
  • These case studies will help to identify patients who can qualify for clinical trials.
  • Ultimately, the goal of the brain tumor board is to improve the overall quality of care for pediatric brain tumor patients across the state.

During the last 20 years, there have been only three cancer medications specifically developed for children.

20% percent of pediatric cancers are still without a cure. Many of these patients are children with brain and spinal cord tumors, which carry an undue proportion of mortality and long-term side effects when compared to other cancers.

2/3 of childhood cancer patients will have long-lasting chronic conditions from treatment

Other programs funded through Tackle Kids Cancer include:

Developmental Therapeutics Program

  • The Developmental Therapeutics Program is the only comprehensive pediatric phase one and two trial program in New Jersey.
  • This program will explore new drugs for patients with cancer; especially those with rare, advanced, and incurable cancers whom traditional therapies have failed.

Transplant Clinical Trials Program

  • The Children’s Cancer Institute is New Jersey’s only pediatric bone marrow transplant center.
  • The Transplant Clinical Trials Program focuses on improving cure rates as well as minimizing the short- and long-term side effects for children going through a bone marrow transplant.

Cure and Beyond Program

  • This program, the most comprehensive in New Jersey, focuses on long-term health, emotional and social issues specific to pediatric cancer survivors.